"Lay the Favorite" follows unpredictable dreamer Beth (Rebecca Hall) as she goes from in-home stripper in Tallahassee to gambler's assistant in Las Vegas, working for Dink (Bruce Willis), one of the most successful sports gamblers in the business. She takes to the work like a natural, but makes the risky bet of falling for Dink, much to the chagrin of his retired showgirl wife Tulip (Catherine Zeta-Jones). That bet goes south, and a triangular war ensues.